New Brunswick™ BioFlo® 510

BioFlo 510 to kompaktowy system z możliwością sterylizacji na miejscu nadający się idealnie do procesów produkcji pilotażowej lub o małej skali. Jego modularne funkcje i szeroki wybór opcji standardowych zapewnia dostateczną elastyczność, aby dostosować go do większości wymagań przeprowadzanych procesów.

Gas flow
› Rotametr:
0 - 3 SLPM
0 - 64 SLPM
0 - 32 SLPM
› Various combinations of 2, 3, or 4 TMFCs:
0.06 - 3 SLPM
0.6 - 32 SLPM
0.3 - 15 SLPM
1 - 64 SLPM
› Overlay with TMFC (0 - 15 or 0 - 32 SLPM)
› Air Wash System with TMFC (0 - 15 or 0 - 32 SLPM)
› Overlay Valve only

Exhaust line
› Exhaust Condenser
› Automatic Pressure Control

Impellers
› Rushton Type – Used commonly for robust cell lines such as bacteria, yeast and algae, where maximum OTR is desired. Provided as standard on BioFlo 510 fermentors
› Pitched Blade – Commonly used with mammalian, insect or other shear sensitive cell lines for batch, fed-batch, or continuous cultures. Produces axial and radial mixing
› Pitched Blade with Magnetic Drive – For critical cell culture applications
› Marine Blade – Commonly used with mammalian, insect or other shear sensitive cell lines for batch, fed-batch, or continuous cultures. Produces axial mixing
› Spin Filter – For Suspension or Microcarrier cultures where a dip tube inside the filter withdraws cell media as harvest or waste
› Cell Lift – Specially designed to provide uniform circulation for both Suspension and Microcarrier cultures. Can be used with optional decanting columns for perfusion cultures (40 L only)
› Packed-Bed Basket Impeller – For secreted products from anchorage dependent and suspension cells, this impeller immobilizes cells in a bed of Fibra-Cel® disks to provide extremely high cell densities (40 L only)

Probes
› Single or Redundant pH/DO Control Systems
› Redox Control System
› Foam/Level Detection System

Addition and sampling
› Resterilizable Sample Valve
› Resterilizable Addition Valves (4 max.)
› Resterilizable Addition/Harvest Valve with Dip Tube (2 max.)
› 3.8 cm Sanitary Fitting 7-Port Septum
› Addition Vessels (Glass / Stainless Steel)
› Decanters
› Sterile Sampling Assembly (Kit of 3)

SCADA software (see page ???)
› BioCommand® Track and Trend
› BioCommand Batch Control
› BioCommand Batch Control Plus

Validation
› Basic Package
› Basic Plus Package
› Enhanced Package

Utility regulator & pre-filter kits
› Process Air Pre-Filter/Regulator Kit
› Instrument Air Pre-Filter/Regulator Kit
› Water Pre-Filter/Regulator Kit
› Process Steam Pre-Filter/Regulator Kit
› Utility Steam Pre-Filter/Regulator Kit
› Utility Connection Kit

Additional options
› Allen Bradley™ CompactLogix™ PLC Control System
› Sprayballs for clean-in-place of Vessel
› External Variable Speed Pumps
› External Scales
› 8-Port Serial Controller (RS-232)
› Spare Parts Kits
› Preventative Maintenance Kits
› Mobile Skid
› System Passivation